MetforminRx · single

Metformin

Live longer, function better.

Starting at

$25/mo

LegitScript certifiedHIPAA compliantAICPA SOC 2 Type II certifiedISO 27001 information security
Fast, free shipping with all plans·
100% online, fully confidential·
US board-certified physicians·
Upfront pricing, no hidden fees·
Fast, free shipping with all plans·
100% online, fully confidential·
US board-certified physicians·
Upfront pricing, no hidden fees·
Fast, free shipping with all plans·
100% online, fully confidential·
US board-certified physicians·
Upfront pricing, no hidden fees·
Metformin

About

Metformin

Caloric restriction mimetic with decades of safety data, used off-label for metabolic health and longevity. Activates AMPK and supports autophagy.

What to expect

The timeline

01

Week 1–2

Blood sugar and appetite control

02

Week 4+

Sustained energy, fat loss, mental clarity

Metabolic balance, daily

  • Enhances insulin sensitivity
  • May reduce visceral fat
  • Supports mitochondrial function
  • May reduce risk of age-related diseases
  • Activates AMPK / autophagy pathways

Be informed

Possible side effects

Every prescription has trade-offs. Your physician reviews these with you before approving treatment.

NauseaDiarrheaGasMetallic tasteB12 deficiency (annual check recommended)Lactic acidosis (rare)

Your questions, answered

Frequently asked questions

    • Start with 500mg once daily, gradually titrate up to 1000–2000mg daily if tolerated
    • Week 1–2: Improved blood sugar and appetite control
    • Week 4+: Enhanced energy, fat loss, cognitive clarity
    • Full anti-aging and metabolic benefits seen with consistent, long-term use
    • Best when combined with fasting, low-glycemic nutrition, and exercise
    • Missed dose? Skip and resume at the next scheduled time—do not double up
  • Common (Typically transient):

    • Nausea
    • Diarrhea
    • Gas or bloating
    • Metallic taste

    Less Common / Monitor If Present:

    • Vitamin B12 deficiency (check annually)
    • Lactic acidosis (rare; risk higher in kidney/liver impairment or alcohol abuse)
    • Decreased appetite or mild fatigue

    Precautions:

    • Not recommended in patients with eGFR <30 mL/min
    • Caution with alcohol or severe calorie restriction
    • Monitor B12 annually with long-term use
    • Take with food to reduce GI side effects