Rx · singleMetformin
Live longer, function better.
Starting at
$25/mo




Fast, free shipping with all plans·
100% online, fully confidential·
US board-certified physicians·
Upfront pricing, no hidden fees·
Fast, free shipping with all plans·
100% online, fully confidential·
US board-certified physicians·
Upfront pricing, no hidden fees·
Fast, free shipping with all plans·
100% online, fully confidential·
US board-certified physicians·
Upfront pricing, no hidden fees·
About
Metformin
Caloric restriction mimetic with decades of safety data, used off-label for metabolic health and longevity. Activates AMPK and supports autophagy.
What to expect
The timeline
01
Week 1–2
Blood sugar and appetite control
02
Week 4+
Sustained energy, fat loss, mental clarity

Metabolic balance, daily
- Enhances insulin sensitivity
- May reduce visceral fat
- Supports mitochondrial function
- May reduce risk of age-related diseases
- Activates AMPK / autophagy pathways
Be informed
Possible side effects
Every prescription has trade-offs. Your physician reviews these with you before approving treatment.
NauseaDiarrheaGasMetallic tasteB12 deficiency (annual check recommended)Lactic acidosis (rare)
Your questions, answered
Frequently asked questions
- Start with 500mg once daily, gradually titrate up to 1000–2000mg daily if tolerated
- Week 1–2: Improved blood sugar and appetite control
- Week 4+: Enhanced energy, fat loss, cognitive clarity
- Full anti-aging and metabolic benefits seen with consistent, long-term use
- Best when combined with fasting, low-glycemic nutrition, and exercise
- Missed dose? Skip and resume at the next scheduled time—do not double up
Common (Typically transient):
- Nausea
- Diarrhea
- Gas or bloating
- Metallic taste
Less Common / Monitor If Present:
- Vitamin B12 deficiency (check annually)
- Lactic acidosis (rare; risk higher in kidney/liver impairment or alcohol abuse)
- Decreased appetite or mild fatigue
Precautions:
- Not recommended in patients with eGFR <30 mL/min
- Caution with alcohol or severe calorie restriction
- Monitor B12 annually with long-term use
- Take with food to reduce GI side effects

